Intro
- Lung lesions
https://www.prrs.com/prrsv-cross-protection-studies - Efficacy evaluation of INGELVAC PRRS® MLV against a PRRSV 1-4-4 L1C.5 variant challenge
Philips et al.; AASV 2025 - Efficacy of Ingelvac PRRS® MLV against a heterologous PRRSV 1-7-4 RFLP challenge
A. Patterson et al.; AASV 2017 - NADC30 lung lesions
Efficacy of the Synergy Between Live-Attenuated and Inactivated PRRSV Vaccines Against a NADC30-Like Strain of Porcine Reproductive and Respiratory Syndrome Virus in 4-Week Piglets; Li et al.; Front. Vet. Sci., 2022 - NADC34 lung lesions
Protective evaluation of the commercialized porcine reproductive and respiratory syndrome virus vaccines in piglets challenged by NADC34-like strain; Liu et al.; Front. Microbiol 2024 - Safety and early onset of immunity with a novel European porcine reproductive and respiratory syndrome virus vaccine in young piglets
Michael Piontkowski et al.; Can J Vet Res 2016 - Safety and early onset of immunity with a novel European porcine reproductive and respiratory syndrome virus vaccine in young piglets
Michael Piontkowski et al.; Can J Vet Res 2016 - Efficacy of commercial PRRS MLV vaccine in reducing the impact of a virulent PRRS1 Rosalia challenge
Vilalta et al.; EPSHM 2026 - Belarus mortality
Pathogenesis and antigenic characterization of a new East European subtype porcine reproductive and respiratory syndrome virus isolate; Karniychuk et al.; BMC Vet Res. 2010 - China mortality
Recombinant characterization and pathogenicity of a novel L1C RFLP-1-4-4 variant of porcine reproductive and respiratory syndrome virus in China; Huang et al.; Vet Res 2024
Origin of highly pathogenic porcine reproductive and respiratory syndrome virus, China; Tong-Qing et al.; Emerg Infect Dis. 2010
Emergence of a highly pathogenic porcine reproductive and respiratory syndrome virus in the Mid-Eastern region of China; Li Y et al.; Vet J. 2007 - Austria mortality
Emergence of a virulent porcine reproductive and respiratory syndrome virus (PRRSV) 1 strain in Lower Austria; Sinn LJ et al.; Porcine Health Manag. 2016 - US mortality
Swine Health Information Center. Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus. Updated July 2021.
https://www.swinehealth.org/wp-content/uploads/2024/01/shic-factsheet-hp-prrsv-2021Jul13.pdf
Trevisan et al.; Microbiol Resour Announc 2021 - Spain mortality
A Spanish Porcine Reproductive and Respiratory Syndrome Virus 1 Strain Is Highly Virulent in Pigs Under Experimental Conditions; Curto et al.; Transboundary and Emerging Diseases 2025 - Economic impact USA
Economic impact of productivity losses attributable to porcine reproductive and respiratory syndrome virus in United States pork production, 2016–2020; Osemeke et al.; Prev Vet Med. 2025 - Daily growth
Examination of viraemia and clinical signs after challenge with a heterologous PRRSV strain in PRRS Type 2 MLV vaccinated pigs: A challenge-dose study; Haiwick et al.; PLoS One 2018
Step 1
- Trends
Dr. Bob Morrison’s Swine Health Monitoring Project: National PRRS incidence/prevalence: July 2025 – June 2026 - Wean to finish mortality
Magalhaes et al.; AASV 2021 - Personal communication
Prof. Linhares, POMP project data
Step 2
- https://fieldepi.org/sdrs/dashboards/
- Boehringer Ingelheim Vetmedica PRRS Ctrl 2.0; Daniel C. L. Linhares, Marius Kunze
Step 3
- Biosecurity
The biosecurity status and its associations with production and management characteristics in farrow-to-finish pig herds; Postma et al.; Animal 2016
Improvements in swine herd biosecurity reduce the incidence risk of PRRSV in breeding herds in the Midwestern United States; Dee et al.; J Am Vet Med Assoc 2024 - A scoping review of knowledge, attitudes, and practices in swine farm biosecurity in North America
Chepkwony et al.; Front Vet Sci 2025 - Pig flow
Effect of Phase Feeding, Space Allowance and Mixing on Productive Performance of Grower-Finisher Pigs; Camp Montoro et al.; Animals 2022 - Simultaneous infections
Synergistic effects of sequential infection with highly pathogenic PRRSV and PCV2; Fan et al.; Virol J 2013 - Multiple strains
Comparison of virus detection, productivity, and economic performance between lots of growing pigs vaccinated with two doses or one dose of PRRS MLV vaccine; Moura et al.; Prev Vet Med 2022 - In-use stability of PRRS MLVs when mixed with PCV2 vaccines
Duran and Strachan; Leman Conference 2021 - Vaccine storage issues
- Vaccine dosing
Silva; PRRS management workshop ISU 2025 - Transport
Modelling contamination of trucks used in the shipment of pigs infected with PRRSV; Thakur et al.; J Swine Health Prod 2017 - Labor
Assessment of the Relationship Between Bioexclusion Practices Applied in Wean-to-Harvest Sites and PRRS Outbreaks; Musskopf et al.; Vet Sci 2025
Interpretable machine learning applied to on-farm biosecurity and PRRSV; Sykes et al.; Transboundary and Emerging Diseases 2022
Step 4
- Biosecurity
Porcine Circovirus Type 2 (PCV-2) Coinfections in US Field Cases of PMWS; Pallarés et al.; J Vet Diagn Invest 2002
Experimental infection of colostrum deprived piglets with PCV2 and PRRSV potentiates PCV2 replication; Allan et al.; Arch Virol 2000
Experimental reproduction of severe disease in CD/CD pigs concurrently infected with PCV2 and PRRSV; Harms et al.; Vet Pathol 2001 - Common issues
Biosecurity status and associations with production characteristics in farrow-to-finish pig herds; Postma et al.; Animal 2016 - Transport
Modelling contamination of trucks used in the shipment of pigs infected with PRRSV; Thakur et al.; J Swine Health Prod 2017 - Labour
Assessment of the Relationship Between Bioexclusion Practices Applied in Wean-to-Harvest Sites and PRRS Outbreaks; Musskopf et al.; Vet Sci 2025
Step 5
- Stable example
Implementation, measurement and return on investment of biosecurity against PRRS on sow reproductive parameters in a high-density pig area in Spain; Blasco et al.; data on file
Maximizing the Chances of Success for PRRS Area Regional Control and Elimination Programs: A 5-Step Process in Practice; Rathkjen and Dall; J Microb Biochem Technol 2018